Comparative study between the effect of neural versus intra-articular dextrose prolotherapy on pain and disability in patients with knee osteoarthritis

Abstract Background Osteoarthritis (OA) is a degenerative disease which presents with joint pain and stiffness reduced mobility. Knee OA the commonest cause of disability in adults. Dextrose prolotherapy new option used to treat mild-to-moderate knee OA. Neural (NPT) multiple small injections under skin targeting painful areas natural substances. The aim work was evaluate compare neural versus intra-articular dextrose effect on relieving improving Results VAS WOMAC scores improved significantly immediately at 3 6 months, respectively, group I compared II ( P < 0.001). decrease all Western Ontario McMaster Universities Index (WOMAC) along follow-up period comparison baseline statistically significant In II, only significantly. ROM showed insignificant increase both groups months assessment. On follow-up, range motion increased reached significance = .002). Conclusion periarticular (neural) very effective cheap therapy for good patient selection. relieves improves function patients osteoarthritis when thus avoiding hazards injections.